Empa reg study

Empagliflozin, Cardiovascular Outcomes, and Mortality in ...

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In the EMPA-REG OUTCOME trial, we examined the effects of empagliflozin, as compared with placebo, on cardiovascular morbidity and mortality in patients with type 2 diabetes at high risk for ...

Empagliflozin, Cardiovascular Outcomes, and Mortality in ...

Empagliflozin, Cardiovascular Outcomes, and Mortality in ...

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EMPA-REG OUTCOME ClinicalTrials.gov number, NCT01131676.) ABSTRACT Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes ...

Empagliflozin, Cardiovascular Outcomes, and Mortality in ...

SGLT2 Inhibitors and Cardiovascular Risk: Lessons Learned ...

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5/1/2016 · The decrease in systolic/diastolic blood pressure in the EMPA-REG OUTCOME study was ∼5/2 mmHg, and was maintained throughout the 3.1-year study duration. Such a decrease in blood pressure could contribute to the reduction in CV events in the EMPA-REG OUTCOME study.

SGLT2 Inhibitors and Cardiovascular Risk: Lessons Learned ...

The EMPA-REG outcome study: critical appraisal and ...

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6/4/2016 · The Empa-Reg outcome is a rewarding study with respect to other clinical trials comparing a specific anti-hyperglycemic drugs vs placebo in terms of CV endpoints. It is difficult to compare studies performed in different historical periods, with different aims, and in patients with different clinical characteristics and concomitant treatments; however, an attempt to compare Empa-Reg outcome ...

The EMPA-REG outcome study: critical appraisal and ...

EMPA-REG OUTCOME: The Endocrinologist's Point of View ...

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The Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients–Removing Excess Glucose (EMPA-REG OUTCOME), the cardiovascular outcome trial investigating the sodium glucose cotransporter 2 (SGLT2) inhibitor empagliflozin, was the first clinical study of a glucose-lowering agent to demonstrate superiority for the ...

EMPA-REG OUTCOME: The Endocrinologist's Point of View ...

EMPA-REG OUTCOME | boehringer-ingelheim.com

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11/14/2016 · About the EMPA-REG OUTCOME ® Trial EMPA-REG OUTCOME ® was a long-term, multicentre, randomised, double-blind, placebo-controlled trial of more than 7,000 patients, from 42 countries, with type 2 diabetes and established cardiovascular disease. 3

EMPA-REG OUTCOME | boehringer-ingelheim.com

BI 10773 (Empagliflozin) Cardiovascular Outcome Event ...

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5/27/2010 · BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME). The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.

BI 10773 (Empagliflozin) Cardiovascular Outcome Event ...

The EMPA-REG study: What has it told us?

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EMPA-REG (Zinman et al., 2015) is the first study to conclusively demonstrate that a medication developed to reduce glycemia (Abdul-Ghani, Norton, & DeFronzo, 2011) in patients with type 2 diabetes mellitus (T2DM) decreases cardiovascular events. In 7020 T2DM patients with established cardiovascular ...

The EMPA-REG study: What has it told us?

After EMPA-REG: Docs Dissect Diabetes Study, Discuss ...

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Doctors tried to make sense of the "unique" finding of the EMPA-REG OUTCOME study, which showed a mortality benefit for empagliflozin, but admitted the trial posed more questions than it answered.

After EMPA-REG: Docs Dissect Diabetes Study, Discuss ...

Empagliflozin Cardiovascular Outcome Event Trial in Type 2 ...

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The EMPA-REG OUTCOME trial showed that empagliflozin is superior to placebo in improving glycemic control and reducing CV events including mortality in patients with DM2 and established CV disease. Patients were randomized in a 1:1:1 fashion to either empagliflozin 10 mg (n = 2,345), 25 mg (n ...

Empagliflozin Cardiovascular Outcome Event Trial in Type 2 ...

Outcomes - Virtual Meeting | EASD

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Session: Results of the EMPA-REG OUTCOME™ Study Stockholm 2015 Hellerström 17. September 2015 17:40 - 18:10 9799 viewers Click to play. Kevin Foley Diet interacts with host NOD2 genotype to control blood glucose and the gut microbiota Steps. 1 ...

Outcomes - Virtual Meeting | EASD

EMPA-REG OUTCOME: The Nephrologist's Point of View ...

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The cardiovascular and renal outcomes data from EMPA-REG OUTCOME have been described.21, 22 Briefly, the study population included patients with T2DM, established cardiovascular disease, and an estimated glomerular filtration rate (eGFR) ≥30 mL/min/1.73 m 2.21, 22 Patients were randomized (N = 7020) to receive either empagliflozin (10 mg or 25 mg) or placebo once daily, in addition to ...

EMPA-REG OUTCOME: The Nephrologist's Point of View ...

Understanding EMPA-REG OUTCOME - The Lancet Diabetes ...

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We have known for some time that individuals with diabetes are more likely to develop heart failure and that a substantially greater number, roughly 50% of patients with type 2 diabetes, have ostensibly asymptomatic diastolic dysfunction on echocardiography.1 Rather than truly being asymptomatic, however, patients with diastolic dysfunction are able to modify their lifestyle to avoid ...

Understanding EMPA-REG OUTCOME - The Lancet Diabetes ...

Understanding EMPA-REG OUTCOME - The Lancet Diabetes ...

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The EMPA-REG OUTCOME study,1 in which the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin showed impressive benefits on cardiovascular mortality, all-cause mortality, and hospital admission for heart failure, could change type 2 diabetes management in years to come.2 The remarkable effect size and rapid onset (<3 months) were unexpected, which suggests a need for an …

Understanding EMPA-REG OUTCOME - The Lancet Diabetes ...

Sanjay Kaul On The Empa-Reg Outcome Study - CardioBrief

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9/17/2015 · The really big medical news today is the publication of the highly anticipated Empa-Reg Outcome study in the New England Journal of Medicine. It is the first large clinical trial with a diabetes drug (empagliflozin, Jardiance) to demonstrate a significant reduction in cardiovascular outcomes.

Sanjay Kaul On The Empa-Reg Outcome Study - CardioBrief

EMPA-REG Renal results. — NephJC

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6/24/2016 · That is until last November when EMPA-REG investigators revealed the renal results from their cardiovascular trial at Kidney Week 2015. EMPA-REG was a post marketing study demanded by the FDA to look at cardiovascular outcomes for patients taking the SGLT-2 inhibitor, empagliflozin, an oral hypoglycemic medication.

EMPA-REG Renal results. — NephJC

Cardiovascular Outcomes and Safety of Empagliflozin in ...

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Peripheral arterial disease and risk of cardiac death in type 2 diabetes: the Fremantle Diabetes Study. Diabetes Care. ... and On behalf of the EMPA-REG OUTCOME Investigators. Vol. 137, No. 2 September 2017. Cardiovascular Safety, Long‐Term Noncardiovascular Safety, and Efficacy of Sodium–Glucose Cotransporter 2 Inhibitors in Patients With ...

Cardiovascular Outcomes and Safety of Empagliflozin in ...

The EMPA-REG OUTCOME Trial - YouTube

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9/6/2016 · Household sharing included. Live TV from 60+ channels. No cable box required. Cancel anytime.

The EMPA-REG OUTCOME Trial - YouTube

Effects of empagliflozin on risk for cardiovascular death ...

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Enter the EMPA-REG Study, published last November in the New England Journal of Medicine. Does this trial finally provide evidence that one of these newer diabetes drugs does more than just ...

Effects of empagliflozin on risk for cardiovascular death ...

Caution Warranted on EMPA-REG Results | Medpage Today

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6/19/2014 · The EMPA-REG OUTCOME™ trial was designed to determine the long-term CV safety of empagliflozin in patients with T2DM and to investigate its potential cardioprotective effects, as well as impact on microvascular outcomes, in a dedicated study …

Caution Warranted on EMPA-REG Results | Medpage Today

Rationale, design, and baseline characteristics of a ...

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Empa conducts cutting-edge materials and technology research, generating interdisciplinary solutions to major challenges faced by industry, and creates the necessary scientific basis to ensure that our society develops in a sustainable manner. As part of the ETH Domain, …

Rationale, design, and baseline characteristics of a ...
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